Lamin B Protein

Lamin b receptor lbr is an integral membrane protein of the interphase nuclear envelope ne.

Lamin b protein. The n terminal end resides in the nucleoplasm binding to lamin b and heterochromatin with the interactions disrupted during mitosis. Lamin b1 often called lamin b in early studies was the first mammalian protein recognized as being isoprenylated 21 22. Lamin b1 antibody rabbit polyclonal from proteintech validated in western blot wb immunoprecipitation ip immunohistochemistry ihc immunofluorescence if flow cytometry fc chimmunoprecipitation ip enzyme linked immunosorbent assay elisa applications. This suggests that the common ancestor of these lamin types was a b type lamin.

Function maintenance of nuclear shape. Due to their properties as a type of if protein lamins provide support for maintaining the shape of the nucleus. Lamin b1 is a protein that in humans is encoded by the lmnb1 gene. The nuclear lamina consists of a two dimensional matrix of proteins located next to the inner nuclear membrane.

Lamin b1 is widely assumed to be expressed by all cell types. The lamin family of proteins make up the matrix and are highly conserved in evolution. Different regions domains of this protein give it two distinct functions. The lbr gene provides instructions for making a protein called the lamin b receptor.