Lamin C Antibody

These proteins are found in many different cell types in three different forms a b and c.

Lamin c antibody. Lamin a and c are detected. The protein may also be known as lamin c dhe lamin a cdcd1 cddc and cmd1a. In humans this protein is encoded by the gene lmna. The expected protein mass is 74 1 kda but there are 6 reported isoforms.

Lamins a and c are alternatively spliced versions of the lmna gene. Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. This antibody can also be used in indirect immunofluorescence 1 2 μg ml using hela cells rat nrk and mouse 3t3 cells. These proteins are found in many different cell types in three different forms a b and c.

A unique family of cysteine proteases has been described that differs in sequence structure and substrate. Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. Performed under reducing conditions. Cleaved fragments of lamin a may form additional bands at 45 50 kda.

Raised against porcine lamin preparation. Lamin a c antibodies. Lamin a c antibody e 1 is available as both the non conjugated anti lamin a c antibody form as well as multiple conjugated forms of anti lamin a c antibody including agarose hrp pe fitc and multiple alexa fluor conjugates. The cellular localization is predicted to be nuclear.

Lamin a c antibody detects endogenous levels of total full length lamin a and lamin c 70 kda as well as the small fragment of lamin a and lamin c resulting from cleavage at aspartic acid 230 28 kda. 70 kda ab8984 was used at a 1 100 dilution against human fibroblast lysate. Lamin c is a reported alias name for the human gene lmna or lamin a c. The 664 amino acid protein is a member of the intermediate filament family.

Anti lamin a lamin c antibody 131c3 nuclear envelope marker ab8984 at 1 100 dilution human fibroblast cell lysate at 15 µl developed using the ecl technique. Lamins a and c are alternatively spliced versions of the lmna gene. The specificity of the lamin a c pab was validated in lamin hela by wb fig 2d. Species predicted to react based on 100 sequence homology.

Lamin a c antibody 636 is a mouse monoclonal igg 2b kappa light chain provided at 200 µg ml. The lamin a c pab antibody recognized both endogenous and recombinant lamin a and detected both pre lamin a and mature lamin a. Listed below are anti lamin c antibodies from multiple suppliers.