Lamin B Antibody

The protein may also be known as adld lmnb and lmn2. I m looking for human lamin antibodies that might cross react with drosophila lamins. In humans this protein is encoded by the gene lmnb1.

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Lamin B1 Antibody B 10 Scbt Santa Cruz Biotechnology

Human Lamin B1 Antibody Mab8525 100 R D Systems

Human Lamin B1 Antibody Af8525 R D Systems

Anti Lamin B1 Antibody Ab65986 Abcam

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Anti lamin b1 antibody b 10 is recommended for detection of lamin b1 of mouse rat and human origin by wb ip if and elisa.

Lamin b antibody. Showing 1 2 of 2 faqs. Lamin a and c are cleaved by caspases into large 41 50 kda and small 28 kda fragments which can be used as markers for apoptosis 4 5. Lamin b1 is also cleaved by caspases during apoptosis 9. Type b lamins consist of lamin b1 and b2 encoded by separate genes 6 8.

Specific for an epitope mapping between amino acids 559 586 at the c terminus of lamin b1 of mouse origin. Lamin b1 and lamin b antibodies are extremely useful as nuclear loading controls for use with nuclear extracts. Lamin b1 antibody b 10 is a mouse monoclonal igg 1 kappa light chain provided at 200 µg ml. The blot was probed with anti lamin b1 recombinant rabbit monoclonal antibody product 702972 1 1000 dilution and detected by chemiluminescence using goat anti rabbit igg h l superclonal secondary antibody hrp conjugate product a27036 1 4000 dilution.

Variants of this antigen may also be found in other species including canine porcine monkey mouse. Lamin b1 will also be removed from a nuclear prep if the nuclear membranes are spun out. When using lamin b1 antibodies as nuclear loading controls be aware that in apoptotic cells lamin b1 is cleaved kottke tj et al. I ve found a few that i m interested in one of which comes in a smaller sample size.

The reported amino acid length is 586 and the expected mass is 66 4 kda. Faqs for lamin b1 antibody nbp1 42594. A 66 kda band corresponding to lamin b1 was observed across the cell lines tested. Anti lamin b1 antibodies are available from several suppliers.

The other two do not have a smaller size ordering option.