Lamin Antibody Drosophila

Antibodies to lamin b are found in individuals.

Lamin antibody drosophila. Site mapping using a monoclonal antibody. Fisher pa journal of cell science 108 pt 9. Lamin a c antibodies. This is the first human disease attributable to mutations in the gene encoding lamin b1.

Antibody dilution 1 2 000 3. Interphase phosphorylation of the drosophila nuclear lamin. Interphase phosphorylation of the drosophila nuclear lamin. Lamin dm0 is expressed during development while lamin c is expressed in late embryo and somatic cells 7 8.

Lamins a and c are alternatively spliced versions of the lmna gene. Site mapping using a monoclonal antibody. Antibody dilution 1 16 000 6. These proteins are found in many different cell types in three different forms a b and c.

In humans mutations in the gene encoding a type lamins are associated with a spectrum of predominantly tissue specific diseases known as laminopathies. Weber k journal of cell science 108 pt 10. In addition an abnormal nuclear morphology was apparent when cultured cells overexpressed this protein. The drosophila genome possesses two genes encoding lamins lamin c and lamin dm0 which have been designated a and b type respectively based on their expression profile and structural features.

Antibody dilution 1 4 000 4. The antibody was developed using goat anti rabbit igg peroxidase secondary antibody and a chemiluminescent substrate. The other two do not have a smaller size ordering option. Increased expression of lamin b1 in drosophila melanogaster resulted in a degenerative phenotype.

I m looking for human lamin antibodies that might cross react with drosophila lamins. Drosophila melanogasterhas two genes for lamins lmn dm0and lmn c equivalent to the b type and a type genes of vertebrates respectively. Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. Antibody dilution 1 8 000 5.

Antibody dilution 1 32 000 7. Expression of drosophila lamin c is developmentally regulated. I ve found a few that i m interested in one of which comes in a smaller sample size. Analogies with vertebrate a type lamins.

Macalpine dm nucleic acids research 44 15 2016 sep 6. Lamin is a structural nuclear envelope protein of the intermediate filament super family that associates with the nuclear membrane. Methylation of histone h4 lysine 20 by pr set7 ensures the integrity of late replicating sequence domains in drosophila. Showing 1 1 of 1 faqs.

Analogies with vertebrate a type lamins. Faqs for lamin b1 antibody nbp2 59783.